Lichen planus
https://en.wikipedia.org/wiki/Lichen_planus
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References
Cutaneous and mucosal lichen planus: a comprehensive review of clinical subtypes, risk factors, diagnosis, and prognosis 24672362 NIH
Lichen planus (LP) jẹ ipo iredodo igba pipẹ ti o ni ipa lori awọn agbalagba ni awọn ọdun aarin wọn. O le ṣe afihan lori awọ ara tabi awọn membran mucous bi ẹnu, obo, esophagus, apoti ohun, ati awọ oju. LP wa ni awọn ọna oriṣiriṣi ti o da lori bii awọn rashes ṣe wo ati ibiti wọn ti han. Awọn ijinlẹ daba pe awọn iru LP kan, bii awọn ti o kan esophagus tabi oju, le ma ṣe ayẹwo to. Diẹ ninu awọn fọọmu ti LP, bii hypertrophic ati awọn iru erosive ni ẹnu, le jẹ ẹru paapaa ati ṣiṣe ni igba pipẹ. Awọn ifosiwewe miiran bi awọn oogun tabi olubasọrọ pẹlu awọn nkan kan le fa awọn rashes ti o jọra.
Lichen planus (LP) is a chronic inflammatory disorder that most often affects middle-aged adults. LP can involve the skin or mucous membranes including the oral, vulvovaginal, esophageal, laryngeal, and conjunctival mucosa. It has different variants based on the morphology of the lesions and the site of involvement. The literature suggests that certain presentations of the disease such as esophageal or ophthalmological involvement are underdiagnosed. The burden of the disease is higher in some variants including hypertrophic LP and erosive oral LP, which may have a more chronic pattern. LP can significantly affect the quality of life of patients as well. Drugs or contact allergens can cause lichenoid reactions as the main differential diagnosis of LP.
Lichen Planus 10865927Lichen planus jẹ ipo awọ ara ti a samisi nipasẹ purplish, awọn bumps dofun alapin ati awọn abulẹ ti o le fa irẹwẹsi lile. Awọn egbo awọ ara wọnyi le jẹ aibalẹ, paapaa nigbati wọn ba ni ipa lori ẹnu tabi awọn abẹ-ara. Ni awọn iṣẹlẹ ti o lewu, oral lichen planus le paapaa pọ si eewu ti idagbasoke iru kan ti awọ ara. O tun le ni ipa lori awọ-ori ati eekanna. Lakoko ti o jẹ idi ti ọpọlọpọ awọn ọran jẹ aimọ, diẹ ninu le jẹ okunfa nipasẹ awọn oogun kan tabi ikolu arun jedojedo C. Itọju deede jẹ awọn ipara to lagbara fun awọn ọran agbegbe ati awọn sitẹriọdu ẹnu fun awọn ti o tan kaakiri diẹ sii.
Lichen planus is a skin condition marked by purplish, flat-topped bumps and patches that can cause intense itching. These skin lesions can be distressing, especially when they affect the mouth or genitals severely. In severe cases, oral lichen planus may even increase the risk of developing a type of skin cancer. It can also affect the scalp and nails. While the cause of most cases is unknown, some may be triggered by certain medications or hepatitis C infection. Treatment typically involves strong creams for localized cases and oral steroids for more widespread ones.
Oral lichen planus 32753462 NIH
Lichen planus jẹ ipo kan nibiti eto ajẹsara nfa iredodo, ti o yọrisi awọn ami iyasọtọ lori awọ ara ati awọn membran mucous. O kan nipa 5% ti awọn agbalagba, diẹ sii nigbagbogbo awọn obirin, ati nigbagbogbo bẹrẹ ni ayika ọjọ ori. Ilowosi ẹnu ni a rii ni to 77% awọn ọran, pupọ julọ ni ipa ẹrẹkẹ inu. Nigba ti diẹ ninu awọn eniyan le ma ni rilara eyikeyi aami aisan, awọn miiran le ni iriri irora ati ni wahala pẹlu awọn ounjẹ kan (fun apẹẹrẹ, ekikan, lata) tabi ehin ehin.
Lichen planus is an immune-mediated inflammatory condition leading to characteristic lesions on skin and mucous membranes. It presents in up to 5% of the general adult population with a female predilection (2:1); the onset is most commonly in middle age. Up to 77% of patients with lichen planus have oral disease, with buccal mucosa the most common subsite. The oral lesions may be asymptomatic, although a subset of patients have pain and difficulty tolerating certain foods (e.g., acidic, spicy) and toothpaste.
Lati jẹrisi iwadii aisan ti lichen planus, a le ṣe biopsy awọ kan. Immunofluorescence taara (DIF) le wulo ni awọn alaisan ti o ni awọn ọgbẹ bullous lati ṣe iyatọ ipo naa lati inu arun vesiculobullous autoimmune.